ABC News Live Prime Full Episode: Tue, Oct 20, 2026 | ABC News

In this full episode of ABC News Live Prime, we cover the top stories of the day. Battleground GOP candidates are breaking with Trump policies as they campaign for the midterms. A violent ICE takedown of a US citizen sparks outrage and calls for accountability. Actress Christina Applegate reveals she was misdiagnosed with MS, sharing her journey and advocacy. Anthropic posts an $80 billion loss, raising questions about the tech industry's future. And actor/comedian Katt Williams joins us for an exclusive interview. Our team of correspondents and analysts provides in-depth reporting and context on these pressing issues, ensuring you stay informed about the events shaping our world. From politics to entertainment, we bring you the stories that matter. ABC News Live Prime is your source for breaking news, exclusive interviews, and 24/7 live streaming coverage. Subscribe to ABC News on YouTube for more daily content and download the ABC News app for the latest headlines and alerts.