Nightline Full Broadcast: Tupac's Legacy, Linda Cardellini's New Role, Elizabeth Holmes Doc

In this full broadcast of Nightline from Friday, October 16, 2026, the show features a range of segments. First, Tupac Shakur's brother reflects on the rapper's enduring legacy, sharing personal memories and insights into his impact on music and culture. The interview offers a rare glimpse into the life of the iconic artist. Next, actress Linda Cardellini discusses her role in the new 'Friday the 13th' prequel series, where she gets bloody in a thrilling performance. Cardellini talks about the challenges of the role and the appeal of the horror genre. The segment includes behind-the-scenes footage. Finally, a new documentary on Elizabeth Holmes hits theaters, exploring the rise and fall of the Theranos founder. The film delves into the scandal and its aftermath, with interviews and archival footage. Nightline provides in-depth coverage of these stories and more.